例句與造句

1. One end of the Ig domain has a section called the complementarity determining region that is important for the specificity of antibodies for their ligands.
2. A number of antibody proteins have RLR nests within the hairpin loops of their H-chain CDRs ( complementarity determining regions ) bound to a carboxylate side chain.
3. The complementarity determining regions of 5.11A1 were cloned into the framework of human IgG and combined with IgG1 ( TGN1112 ) or IgG4 ( TGN1412 ) constant regions.
4. Libraries of antibody Fab ( fragment, antigen binding ) regions were generated with codon substituted variations of the antibody complementarity determining regions ( CDRs ) inserted into human antibody light and heavy chain germline frameworks ( data on file at Mentrik Biotec ).
5. The molecule was genetically engineered by transfer of the complementarity determining regions ( CDRs ) from heavy and light chain variable region sequences of a monoclonal mouse anti-humanC28 [ sic ] antibody ( 5.11A1, Luhder et al ., 2003 ) into human heavy and light chain variable frameworks.
6. It's difficult to find complementarity determining regions in a sentence. 用complementarity determining regions造句挺難的
7. The variable domain of both the TCR ?-chain and ?-chain each have three hypervariable or complementarity determining regions ( CDRs ), whereas the variable region of the ?-chain has an additional area of hypervariability ( HV4 ) that does not normally contact antigen and, therefore, is not considered a CDR.
8. Increases in antibody-antigen binding strength have been achieved by introducing mutations into the complementarity determining regions ( CDR ), using techniques such as chain-shuffling, randomization of complementarity-determining regions and antibodies with mutations within the variable regions induced by error-prone E . coli mutator strains and site-specific mutagenesis.
9. Part of the variable regions may also be substituted, in which case it is called " humanized " and "-zu-" is used; typically, everything is replaced except the complementarity determining regions ( CDRs ), the three loops of amino acid sequences at the outside of each variable region that bind to the target structure.